Abstract |
Repeat insult patch testing of the quinoline dyes, D & C Yellow No. 10 ( Acid Yellow No. 3) and D & C Yellow No. 11 ( Solvent Yellow No. 33) demonstrated that concentrations as high as 1,000 ppm of the former induced no delayed contact hypersensitivity, whereas, concentrations of 20 ppm and 10 ppm of D & C Yellow No. 11 induced delayed hypersensitivity reactions in human volunteer panelists. No definitive hypersensitivity resulted from testing with 5 ppm of this dye. 2 persons who had been demonstrated to have reacted allergically to the use of a soap bar that contained D & C Yellow No. 11 did not react to the ad libitum use of a soap bar in which this dye was replaced with D & C Yellow No. 10.
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Authors | J E Weaver |
Journal | Contact dermatitis
(Contact Dermatitis)
Vol. 9
Issue 4
Pg. 309-12
(Jul 1983)
ISSN: 0105-1873 [Print] England |
PMID | 6684531
(Publication Type: Case Reports, Journal Article)
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Chemical References |
- Quinolines
- quinoline yellow
- 2-((2'-quinolinyl)-1,3-indandione)
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Topics |
- Dermatitis, Contact
(etiology)
- Dose-Response Relationship, Drug
- Female
- Humans
- Hypersensitivity, Delayed
(chemically induced)
- Male
- Middle Aged
- Patch Tests
- Quinolines
(administration & dosage, adverse effects)
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