An open study of pivampicillin (Pondocillin) as a treatment for acute lower urinary tract infection.

Abstract

In a multicentre general practice study 158 females with acute, uncomplicated urinary tract infection received a 5-day course of pivampicillin 500 mg twice-daily (Pondocillin). Significant bacteriological cultures were obtained from forty-one patients before treatment and the original organism was eradicated in thirty-eight of these patients (93%). The mean symptom score was reduced from 7.33 to 1.18. Eleven patients (7%) reported side-effects. One patient ceased treatment after 4 days due to a rash. Pivampicillin, in a convenient twice-daily regimen, was confirmed as an effective treatment for acute lower urinary tract infection.

• Authors: J B Sutton
• Journal: The Journal of international medical research (J Int Med Res) Vol. 11 Issue 6 Pg. 375-9 ( 1983) ISSN: 0300-0605 [Print] England
• PMID: 6653869 (Publication Type: Journal Article)

Chemical References

• Pivampicillin
• Ampicillin

Topics

• Acute Disease
• Adolescent
• Adult
• Ampicillin (analogs & derivatives, pharmacology)
• Bacteria (drug effects, isolation & purification)
• Female
• Humans
• Middle Aged
• Pivampicillin (adverse effects, therapeutic use)
• Urinary Tract Infections (classification, drug therapy, microbiology)