Estrogen accelerates the recovery of the lordosis response after its exhaustion induced by cervical probing.

Abstract

Repetitive flank-perineum palpation combined with probing the vaginal cervix in ovariectomized hormonally untreated rats elicited a mean of 4.2 +/- 0.2 (SEM) successive lordosis responses before the response was exhausted. Two days after a single injection of estradiol benzoate (100 micrograms/kg body wt) in ovariectomized rats, a significantly greater number (7.8 +/- 0.2) of lordosis responses could be elicited before the response was exhausted (P less than 0.01). After this exhaustion, recovery of lordosis responsiveness to this stimulation occurred significantly earlier in the estrogen-treated rats (6 hr) than in the oil-treated rats (60 hr) (P less than 0.01). Several possible mechanisms mediating these effects are proposed.

• Authors: J F Rodriguez-Sierra, B R Komisaruk
• Journal: Hormones and behavior (Horm Behav) Vol. 17 Issue 3 Pg. 302-7 (Sep 1983) ISSN: 0018-506X [Print] United States
• PMID: 6642438 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't, Research Support, U.S. Gov't, Non-P.H.S., Research Support, U.S. Gov't, P.H.S.)

Chemical References

• Estradiol

Topics

• Animals
• Castration
• Cervix Uteri (physiology)
• Estradiol (pharmacology)
• Female
• Ovary (physiology)
• Physical Stimulation
• Posture
• Rats
• Rats, Inbred Strains
• Reflex (physiology)
• Sexual Behavior, Animal (drug effects, physiology)