HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

The effect of O-(beta-hydroxyethyl)-rutoside (HR) on macromolecular leakage, thrombosis and haemostasis in experimental animals.

Abstract
O-(beta-hydroxyethyl)-rutoside (HR) (Venoruton, Zyma AS, Nyon, Switzerland) has been investigated experimentally to evaluate the effect on microvascular permeability and thromboembolism. Permeability to macromolecules is diminished in a hamster cheek-pouch model. Haemostatic plug formation is impaired whereas laser-induced intravascular platelet aggregation is uninfluenced. There is a small but insignificant protection against sodium morrhuate (Eli Lilly and Co., Indianapolis, Indiana) induced femoral vein thrombosis.
AuthorsD Bergqvist, E Svensjö, K E Arfors
JournalUpsala journal of medical sciences (Ups J Med Sci) Vol. 83 Issue 2 Pg. 123-7 ( 1978) ISSN: 0300-9734 [Print] Sweden
PMID664118 (Publication Type: Journal Article)
Chemical References
  • Hydroxyethylrutoside
  • Macromolecular Substances
  • Rutin
  • Sodium Morrhuate
Topics
  • Animals
  • Capillary Permeability (drug effects)
  • Cricetinae
  • Hemostasis (drug effects)
  • Hydroxyethylrutoside (blood, pharmacology, therapeutic use)
  • Macromolecular Substances
  • Male
  • Microcirculation (drug effects)
  • Rutin (analogs & derivatives)
  • Sodium Morrhuate
  • Thrombophlebitis (chemically induced, prevention & control)

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: