Abstract |
We measured the serum-stimulated lipase activity, fatty acid content, and various biochemical parameters in the breast milk of a lactating mother suffering from familial lipoprotein lipase deficiency and of healthy control subjects. Serum-stimulated lipase activity was virtually undetectable in milk from our patient and the total fatty acid content was low. The fatty acid composition differed from normal showing a marked absolute and relative increase in the content of lauric (C12:0) and myristic (C14:0) fatty acids and considerably reduced levels of oleic (C18:1) and especially linoleic (C18:2) acids. Other fatty acid species showed lesser changes in concentration. Besides a reduced calcium concentration in the milk from our patient, other biochemical parameters were not significantly different from control subjects.
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Authors | G M Berger, A Spark, P M Baillie, J Huskisson, G Stockwell, E van der Merwe |
Journal | Pediatric research
(Pediatr Res)
Vol. 17
Issue 10
Pg. 835-9
(Oct 1983)
ISSN: 0031-3998 [Print] United States |
PMID | 6634247
(Publication Type: Case Reports, Journal Article, Research Support, Non-U.S. Gov't)
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Chemical References |
- Fatty Acids
- Fatty Acids, Essential
- Fatty Acids, Nonesterified
- Lipids
- Lipoprotein Lipase
- Calcium
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Topics |
- Adult
- Calcium
(analysis)
- Fatty Acids
(analysis)
- Fatty Acids, Essential
(analysis)
- Fatty Acids, Nonesterified
(analysis)
- Female
- Humans
- Hyperlipoproteinemia Type I
(enzymology)
- Hyperlipoproteinemias
(enzymology)
- Lactation
- Lipids
(analysis)
- Lipoprotein Lipase
(metabolism)
- Milk, Human
(analysis, enzymology)
- Pregnancy
- Pregnancy Complications
(enzymology)
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