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Dipivalyl epinephrine: a new pro-drug in the treatment of glaucoma.

Abstract
The dansyl chloride technique in conjunction with thin layer chromatography and autoradiography has shown that dipivalyl epinephrine is a pro-drug in the human eye. Dipivalyl epinephrine appears to be a more effective epinephrine compound, in that it penetrates the cornea approximately 17 times greater than epinephrine.
AuthorsA I Mandell, F Stentz, A E Kitabchi
JournalOphthalmology (Ophthalmology) Vol. 85 Issue 3 Pg. 268-75 (Mar 1978) ISSN: 0161-6420 [Print] United States
PMID662280 (Publication Type: Journal Article)
Chemical References
  • Carbon Radioisotopes
  • Epinephrine
Topics
  • Aqueous Humor (analysis)
  • Autoradiography
  • Carbon Radioisotopes
  • Chromatography, Thin Layer
  • Cornea (metabolism)
  • Epinephrine (metabolism)
  • Glaucoma (drug therapy)
  • Humans

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