Unusual clinical courses of adult T-cell leukemia in siblings.

Abstract	Two siblings who developed adult T-cell leukemia (ATL) with unusual clinical courses are presented. The brother showed spontaneous remissions at the beginning stage of the disease of 6 years' duration, and the sister remains free of complaints for 6 years without chemotherapy. The patients and 2 of 12 healthy members of their family examined had serum antibodies against ATL-associated antigens (ATLA). The expression of ATLA was observed in the cultured lymphocytes from the patients and one of the family members.
Authors	F Kawano, H Tsuda, K Yamaguchi, H Nishimura, I Sanada, H Matsuzaki, M Ishii, K Takatsuki
Journal	Cancer (Cancer) Vol. 54 Issue 1 Pg. 131-4 (Jul 01 1984) ISSN: 0008-543X [Print] United States
PMID	6609759 (Publication Type: Case Reports, Journal Article)
Chemical References	Antibodies, Monoclonal Antigens, Neoplasm Membrane Glycoproteins thymus-leukemia antigens
Topics	Antibodies, Monoclonal Antigens, Neoplasm (analysis) Cell Separation Female Humans Leukemia (genetics, immunology, pathology) Male Membrane Glycoproteins Middle Aged Pedigree T-Lymphocytes (immunology, pathology)

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