[Choice of treatment in recurrent urinary infections in childhood].

Abstract

Forty-two cases of children showing recurrent urinary tract infection were treated. Three treatment guides were used: the first group of children were given trimetoprim-sulphametoxazole (TMP-SMZ) only, the second and third ones were treated with TMP-SMZ and alternative nitrofurantoine in the former or nalidixic acid in the latter. After treatment a meaning reduction in frequency of urinary tract infection cases (p less than 0.001) were observed. Best results (lesser percentage of failures and lesser number of urinary tract infection cases per month of observation) were achieved in the second and third groups, probably due to a high percentage of resistance cases against TMP-SMZ found during prophylactic treatment (72.07).

• Authors: M Sánchez Bayle, M L Barrio Pérez, M R Estepa Soto, L López Verde
• Journal: Anales espanoles de pediatria (An Esp Pediatr) Vol. 20 Issue 1 Pg. 28-32 (Jan 1984) ISSN: 0302-4342 [Print] Spain
• Vernacular Title: Elección de tratamiento en las infecciones urinarias recurrentes en la infancia.
• PMID: 6608301 (Publication Type: English Abstract, Journal Article)

Chemical References

• Anti-Infective Agents, Urinary
• Drug Combinations
• Nalidixic Acid
• Trimethoprim, Sulfamethoxazole Drug Combination
• Nitrofurantoin
• Trimethoprim
• Sulfamethoxazole

Topics

• Anti-Infective Agents, Urinary (therapeutic use)
• Child
• Child, Preschool
• Drug Combinations (therapeutic use)
• Drug Resistance, Microbial
• Drug Therapy, Combination
• Female
• Humans
• Male
• Nalidixic Acid (therapeutic use)
• Nitrofurantoin (therapeutic use)
• Recurrence
• Sulfamethoxazole (therapeutic use)
• Trimethoprim (therapeutic use)
• Trimethoprim, Sulfamethoxazole Drug Combination
• Urinary Tract Infections (drug therapy, prevention & control)