The efficacy of topical anesthetics in reducing intraoral discomfort.

Abstract

The purpose of this investigation was to compare the effectiveness of three gels in reducing discomfort due to denture irritation. Forty-five subjects experiencing denture soreness were randomly selected. A double-blind format was used. Two of the gels contained 20% of the known pain reliever, while the third gel contained 10%. An unweighted-means and a least-squares analysis of variance were done for the type of gel and pretreatment pain. The results show that the gels were effective in reducing perceived pain for 66% of the subjects. As a result of the analyses, no significant differences were found between gels.

• Authors: G N Graser
• Journal: Oral surgery, oral medicine, and oral pathology (Oral Surg Oral Med Oral Pathol) Vol. 58 Issue 1 Pg. 42-6 (Jul 1984) ISSN: 0030-4220 [Print] United States
• PMID: 6589577 (Publication Type: Comparative Study, Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• Gels
• Benzocaine

Topics

• Administration, Topical
• Benzocaine (administration & dosage, therapeutic use)
• Denture, Complete (adverse effects)
• Denture, Partial, Removable (adverse effects)
• Double-Blind Method
• Evaluation Studies as Topic
• Female
• Gels
• Humans
• Male
• Random Allocation
• Stomatitis (drug therapy)
• Stomatitis, Denture (drug therapy)