[Clinical experience with cefmetazole in the urological field].

Abstract

The clinical effectiveness of Cefmetazole, a new cephamycin antibiotic, was studied in 13 cases of complicated urinary tract infection and in 3 cases of acute simple pyelonephritis. The drug was administrated, in 2 or 4 g doses twice a day, by intravenous drip infusion, for 5 to 10 days. The overall clinical effectiveness rate, based on the UTI efficacy evaluation, was 92% for complicated urinary tract infection and 100% for acute simple pyelonephritis. Among 18 strains isolated, 14 strains were eradicated and 4 strains were replaced. The bacteriological efficacy was 100%. No adverse reaction was noted. Cefmetazole was suggested to be a useful antibiotic for the treatment of urinary tract infections.

• Authors: Y Aga, M Yano, K Ogura
• Journal: Hinyokika kiyo. Acta urologica Japonica (Hinyokika Kiyo) Vol. 29 Issue 4 Pg. 459-63 (Apr 1983) ISSN: 0018-1994 [Print] Japan
• PMID: 6587763 (Publication Type: English Abstract, Journal Article)

Chemical References

• Cephamycins
• Cefmetazole

Topics

• Acute Disease
• Adult
• Aged
• Bacteria (drug effects)
• Cefmetazole
• Cephamycins (pharmacology, therapeutic use)
• Drug Resistance, Microbial
• Female
• Humans
• Male
• Middle Aged
• Pyelonephritis (drug therapy)
• Urinary Tract Infections (drug therapy, microbiology)