Abstract |
The number and fluorescence intensity of fluorescent granules (5-HT storage organelles) of mepacrine-incubated blood platelets of beige mice ( Chediak-Higashi syndrome) are decreased compared to those of control mice platelets. This indicates both quantitative and qualitative changes of the 5-HT organelles, namely a reduced number and a reduced storage capacity, respectively.
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Authors | H P Lorez, M Da Prada |
Journal | Experientia
(Experientia)
Vol. 34
Issue 5
Pg. 663-4
(May 15 1978)
ISSN: 0014-4754 [Print] Switzerland |
PMID | 658263
(Publication Type: Journal Article)
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Chemical References |
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Topics |
- Animals
- Blood Platelets
(metabolism)
- Chediak-Higashi Syndrome
(blood)
- Histocytochemistry
- Mice
- Microscopy, Fluorescence
- Quinacrine
(metabolism)
- Serotonin
(metabolism)
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