[Course of urinary schistosomiasis over 3 consecutive years after treatment with metrifonate in a dry savanna village in Upper Volta].

Abstract

In a dry savanna village in Upper-Volta, after mass treatment with metrifonate (four doses of 7,5 mg/kg at three weeks intervals) checking of the population was carried out for the three following years. In children and adolescents, results show a progressive decline in the cure rate (69.0% one year after treatment, 38.1% three years after treatment) and in egg-output reduction (69.9% one year after treatment, 75.4% three years after treatment). In adults, these two parameters still remain high three years after treatment (90.0% for cure rate and 87.3% for egg-output reduction). The authors point out that in a dry savanna village with a sedentary population and a transmission limited to a small collection of water, chemotherapy even employed alone is an appreciable control method to relieve populations.

• Authors: B Sellin, E Simonkovich, E Sellin, J L Rey, F Mouchet
• Journal: Medecine tropicale : revue du Corps de sante colonial (Med Trop (Mars)) 1984 Oct-Dec Vol. 44 Issue 4 Pg. 357-9 ISSN: 0025-682X [Print] France
• Vernacular Title: Evolution sur trois années consécutives de la schistosomose urinaire après traitement au metrifonate dans un village de savane seche de Haute-Volta.
• PMID: 6542966 (Publication Type: English Abstract, Journal Article)

Chemical References

• Trichlorfon

Topics

• Adolescent
• Adult
• Burkina Faso
• Child
• Child, Preschool
• Follow-Up Studies
• Humans
• Parasite Egg Count
• Schistosomiasis (drug therapy)
• Time Factors
• Trichlorfon (therapeutic use)
• Urine (parasitology)
• Urologic Diseases (drug therapy)