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[Antiamnestic properties of pyrazole dicarboxylic acid derivatives in rats].

Abstract
Eight derivatives of pyrazole dicarboxylic acid (IEM-565, IEM-476, IEM-1332, IEM-474, IEM-373, IEM-440, IEM-1333, IEM-439) have been studied in rats for the ability to abolish the amnesia of passive avoidance behavior induced by electroconvulsive shock IEM-476, IEM-373 and IEM-439 have proved to be the most efficacious.
AuthorsP D Shabanov, I Ia Aleksandrova
JournalFarmakologiia i toksikologiia (Farmakol Toksikol) 1984 Jul-Aug Vol. 47 Issue 4 Pg. 28-30 ISSN: 0014-8318 [Print] Russia (Federation)
Vernacular TitleIzuchenie antiamnesticheskikh svoĭstv proizvodnykh pirazoldikarbonovoĭ kisloty u krys.
PMID6541157 (Publication Type: Comparative Study, English Abstract, Journal Article)
Chemical References
  • Imidazoles
  • Pyrazoles
  • Etimizol
Topics
  • Amnesia (drug therapy, etiology)
  • Animals
  • Conditioning, Classical (drug effects)
  • Drug Evaluation, Preclinical
  • Electroshock
  • Escape Reaction (drug effects)
  • Etimizol (analogs & derivatives, therapeutic use)
  • Humans
  • Imidazoles
  • Male
  • Pyrazoles (therapeutic use)
  • Rats

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