Abstract |
Eight derivatives of pyrazole dicarboxylic acid (IEM-565, IEM-476, IEM-1332, IEM-474, IEM-373, IEM-440, IEM-1333, IEM-439) have been studied in rats for the ability to abolish the amnesia of passive avoidance behavior induced by electroconvulsive shock IEM-476, IEM-373 and IEM-439 have proved to be the most efficacious.
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Authors | P D Shabanov, I Ia Aleksandrova |
Journal | Farmakologiia i toksikologiia
(Farmakol Toksikol)
1984 Jul-Aug
Vol. 47
Issue 4
Pg. 28-30
ISSN: 0014-8318 [Print] Russia (Federation) |
Vernacular Title | Izuchenie antiamnesticheskikh svoĭstv proizvodnykh pirazoldikarbonovoĭ kisloty u krys. |
PMID | 6541157
(Publication Type: Comparative Study, English Abstract, Journal Article)
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Chemical References |
- Imidazoles
- Pyrazoles
- Etimizol
|
Topics |
- Amnesia
(drug therapy, etiology)
- Animals
- Conditioning, Classical
(drug effects)
- Drug Evaluation, Preclinical
- Electroshock
- Escape Reaction
(drug effects)
- Etimizol
(analogs & derivatives, therapeutic use)
- Humans
- Imidazoles
- Male
- Pyrazoles
(therapeutic use)
- Rats
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