Abstract |
Tetanus is enzootic in the free-ranging rhesus monkey colony on Cayo Santiago. The disease accounts for 25% of all mortalities in the population. The high prevalence of tetanus provided a unique opportunity to study the potential roles of geophagia, wounding, and clinical tetanus infections on the development of naturally acquired tetanus antitoxin in rhesus macaques. Eighty-six unvaccinated monkeys, including six that recovered from tetanus, were serosurveyed using a mouse toxin neutralization test. None of the animals had detectable antitoxin titers (less than 0.001 AU/ml), suggesting that natural immunity to tetanus is either rare or nonexistent in the Cayo Santiago colony.
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Authors | M J Kessler, R G Rawlins |
Journal | Journal of medical primatology
(J Med Primatol)
Vol. 13
Issue 6
Pg. 353-7
( 1984)
ISSN: 0047-2565 [Print] Denmark |
PMID | 6520863
(Publication Type: Journal Article, Research Support, U.S. Gov't, P.H.S.)
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Chemical References |
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Topics |
- Animals
- Guinea Pigs
- Humans
- Immunity, Innate
- Macaca
(immunology)
- Macaca mulatta
(immunology)
- Tetanus
(immunology)
- Tetanus Antitoxin
(immunology)
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