Low serum zinc in children with atopic eczema.

Abstract

Serum zinc was measured by atomic absorption spectrophotometry in sixty-five children with atopic eczema and seventy-nine control children. The mean serum zinc of the patients, (11.4 +/- 2.0 mumol/l) was significantly lower than that of the controls (13.7 +/- 2.3 mumol/l, P less than 0.0001). There was no significant correlation between the patients' serum zinc concentration and either the height/weight centile or a subjective assessment of severity and extent of the eczema. Of eleven patients with serum zinc below 10 mumol/l, six had recurrent infections of the skin, a significantly greater proportion than in patients whose serum zinc was 10 mumol/l or above. It is suspected that the decreased plasma zinc concentration in children with eczema is a non-specific consequence of the dermatological disorder, and therefore there is no indication for zinc supplementation.

• Authors: T J David, F E Wells, T C Sharpe, A C Gibbs
• Journal: The British journal of dermatology (Br J Dermatol) Vol. 111 Issue 5 Pg. 597-601 (Nov 1984) ISSN: 0007-0963 [Print] England
• PMID: 6498092 (Publication Type: Journal Article)

Chemical References

• Zinc

Topics

• Adolescent
• Child
• Child, Preschool
• Dermatitis, Atopic (blood, complications)
• Female
• Humans
• Ichthyosis (complications)
• Infant
• Male
• Skin Diseases, Infectious (complications)
• Spectrophotometry, Atomic
• Zinc (blood, deficiency)