[Deferoxamine in hemosiderosis. Fecal iron excretion during continuous subcutaneous infusion].

Abstract

Faecal iron excretion during continuous subcutaneous deferoxamine infusion was measured by flameless atom-absorption spectral photometry in 21 patients with homozygous ss-thalassaemia and one patient with Blackfan-Diamond anaemia. Taking into account faecal and urinary iron excretion, more iron was eliminated than was taken up during transfusion and by intestinal absorption. Urine contained 37.9%, faeces 62.1% of the amount of iron eliminated.

• Authors: N Krüger, H Kijewski, R König, W Tillmann, W Schröter
• Journal: Deutsche medizinische Wochenschrift (1946) (Dtsch Med Wochenschr) Vol. 109 Issue 44 Pg. 1682-5 (Nov 02 1984) ISSN: 0012-0472 [Print] Germany
• Vernacular Title: Deferoxamin bei Hämosiderose. Fäkale Eisenausscheidung während kontinuierlicher subkutaner Infusionen.
• PMID: 6489181 (Publication Type: English Abstract, Journal Article)

Chemical References

• Iron
• Deferoxamine

Topics

• Adolescent
• Child
• Child, Preschool
• Deferoxamine (administration & dosage, therapeutic use)
• Feces (analysis)
• Hemosiderosis (drug therapy, etiology, metabolism)
• Humans
• Injections, Subcutaneous (methods)
• Iron (analysis)
• Male
• Self Administration
• Thalassemia (complications)