Resolution of brain edema in severe brain injury at controlled high and low intracranial pressures.

Abstract	A series of 87 patients with severe brain injury were studied. Intracranial pressure (ICP) monitoring and external ventricular drainage were used to control ICP at high and low levels. Clearance of ytterbium-169-labeled diethylenetriaminepentaacetic acid (169Yb-DTPA), Evans blue dye, and ventricular cerebrospinal fluid protein was measured at the two ICP levels over consecutive periods of 4 hours to confirm clearance of brain edema. The results support the hypothesis that brain edema is in part absorbed in the cerebrospinal fluid via transventricular flow.
Authors	M Cao, H Lisheng, S Shouzheng
Journal	Journal of neurosurgery (J Neurosurg) Vol. 61 Issue 4 Pg. 707-12 (Oct 1984) ISSN: 0022-3085 [Print] United States
PMID	6470780 (Publication Type: Journal Article)
Chemical References	Pentetic Acid Ytterbium
Topics	Adolescent Adult Aged Brain Edema (diagnostic imaging, physiopathology, surgery) Brain Injuries (diagnostic imaging, physiopathology, surgery) Child Drainage Humans Intracranial Pressure Middle Aged Monitoring, Physiologic Pentetic Acid Radionuclide Imaging Ytterbium

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