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Cephalothin induced neutropenia during the treatment of bacterial endocarditis.

Abstract
The occurrence of cephalothin induced neutropenia in 3 patients with infective endocarditis is described. In each patient, withdrawal of cephalothin was followed by rapid haematological recovery. It is apparent that granulocytopenia may frequently occur in patients receiving prolonged, high dose, intravenous cephalothin for the treatment of bacterial endocarditis.
AuthorsS Holt, M M Khan, D A Orlans, E J Epstein
JournalScottish medical journal (Scott Med J) Vol. 23 Issue 2 Pg. 135-9 (Apr 1978) ISSN: 0036-9330 [Print] Scotland
PMID644296 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Cephalothin
Topics
  • Adult
  • Agranulocytosis (chemically induced)
  • Cephalothin (adverse effects)
  • Child, Preschool
  • Endocarditis, Bacterial (drug therapy)
  • Female
  • Humans
  • Male
  • Neutropenia (chemically induced)
  • Streptococcal Infections (drug therapy)

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