[EEG activation using bemegride in the diagnosis of epilepsy. 2. Catamnestic studies].

Abstract

43 patients were evaluated catamnestically 5-10 years after a bemegride test in order to proof its relevance. The bemegride test was considered as diagnostically helpful in 37 cases (86%) based on observations of the course. It had been false negative in four cases (9,3%), and false positive in two cases (4,7%). The occurrence of epileptic attacks is indicated by the activation of regular and irregular spike-wave complexes as well as other specific epileptic discharges. These could be activated by an average threshold of 68,5 mg or 1,09 mg/kg body weight in 86,2% of all patients with epileptic attacks. The threshold dose was lower in cases of primary generalized attacks than in complex focal attacks. The indication for the bemegride test is restricted.

• Authors: P Bülau, W Fröscher
• Journal: EEG-EMG Zeitschrift fur Elektroenzephalographie, Elektromyographie und verwandte Gebiete (EEG EMG Z Elektroenzephalogr Elektromyogr Verwandte Geb) Vol. 15 Issue 3 Pg. 132-7 (Sep 1984) ISSN: 0012-7590 [Print] Germany
• Vernacular Title: EEG Aktivierung mit Bemegrid in der Epilepsie-Diagnostik. Teil 2: Katamnestische Untersuchungen.
• PMID: 6435995 (Publication Type: Case Reports, English Abstract, Journal Article)

Chemical References

• Bemegride

Topics

• Adult
• Bemegride (pharmacology)
• Diagnosis, Differential
• Electroencephalography
• Epilepsy (diagnosis, physiopathology)
• False Positive Reactions
• Female
• Follow-Up Studies
• Humans
• Male
• Seizures (physiopathology)