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Degos' disease: association with anticardiolipin antibodies and the lupus anticoagulant.

Abstract
A woman presented with multiple cerebral thromboses and skin lesions characteristic of Degos' disease. Her serum contained high titres of anticardiolipin antibodies and showed lupus anticoagulant activity, both known to be strong markers of a thrombotic tendency in systemic lupus erythematosus. This finding may have therapeutic implications for this usually fatal disease.
AuthorsH J Englert, C H Hawkes, M L Boey, G J Derue, S Loizou, E N Harris, A E Gharavi, R G Hull, G R Hughes
JournalBritish medical journal (Clinical research ed.) (Br Med J (Clin Res Ed)) Vol. 289 Issue 6445 Pg. 576 (Sep 08 1984) ISSN: 0267-0623 [Print] England
PMID6432197 (Publication Type: Case Reports, Journal Article, Research Support, Non-U.S. Gov't)
Chemical References
  • Antibodies
  • Blood Coagulation Factors
  • Cardiolipins
  • Lupus Coagulation Inhibitor
Topics
  • Adult
  • Antibodies (analysis)
  • Blood Coagulation Factors (analysis, antagonists & inhibitors)
  • Cardiolipins (immunology)
  • Female
  • Humans
  • Lupus Coagulation Inhibitor
  • Skin Diseases (blood, immunology)

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