Abstract |
Eighty unpremedicated female patients undergoing short gynaecological procedures were randomly allocated to four groups and received either alfentanil or fentanyl (double-blind), together with Althesin- oxygen or methohexitone- nitrous oxide'- oxygen. Recovery from anaesthesia was assessed using the post-box test and the deletion of p. There was a significantly greater frequency of vomiting after operation (P less than 0.05) with methohexitone compared with Althesin and with fentanyl compared with alfentanil, and a significantly greater frequency of pain on injection (P less than 0.001) with methohexitone compared with Althesin. The alfentanil groups completed the post-box test significantly earlier after operation than the fentanyl groups (P less than 0.05). We conclude that alfentanil may offer a significant advantage over fentanyl as an analgesic supplement to i.v. anaesthesia for short procedures.
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Authors | M Patrick, B M Eagar, D F Toft, P S Sebel |
Journal | British journal of anaesthesia
(Br J Anaesth)
Vol. 56
Issue 8
Pg. 861-6
(Aug 1984)
ISSN: 0007-0912 [Print] England |
PMID | 6430311
(Publication Type: Clinical Trial, Comparative Study, Journal Article, Randomized Controlled Trial)
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Chemical References |
- Adjuvants, Anesthesia
- Alfentanil
- Fentanyl
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Topics |
- Adjuvants, Anesthesia
- Alfentanil
- Anesthesia, General
- Dilatation and Curettage
- Double-Blind Method
- Female
- Fentanyl
(analogs & derivatives, pharmacology)
- Hemodynamics
(drug effects)
- Humans
- Random Allocation
- Respiration
(drug effects)
- Time Factors
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