Comparison of two different regimens of metronidazole in the treatment of non-specific vaginitis.

Abstract

25 patients with symptoms of non-specific vaginitis have been treated with metronidazole either 2000 mg in a single dose or 400 mg three times daily for 5 days. Diagnosis was settled by 1) identification of G. vaginalis in culture of vaginal secretion, 2) the observation of clue cells in wet smear, 3) a positive amine test on application of potassium hydroxide, and 4) increased pH in the vaginal secretion. Most patients' symptoms and complaints disappeared and at the same time most of the tests used changed from abnormal to normal findings. No side effects were recorded. It is concluded, that metronidazole in either dose was a useful treatment of non-specific vaginitis.

• Authors: B Hagström, J Lindstedt
• Journal: Scandinavian journal of infectious diseases. Supplementum (Scand J Infect Dis Suppl) Vol. 40 Pg. 95-6 ( 1983) ISSN: 0300-8878 [Print] England
• PMID: 6364334 (Publication Type: Clinical Trial, Comparative Study, Journal Article, Randomized Controlled Trial)

Chemical References

• Metronidazole

Topics

• Clinical Trials as Topic
• Female
• Follow-Up Studies
• Gardnerella vaginalis (drug effects)
• Haemophilus Infections (diagnosis, drug therapy)
• Humans
• Metronidazole (administration & dosage)
• Random Allocation
• Time Factors
• Vaginitis (diagnosis, drug therapy)