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Efficacy of ampicillin and cefoxitin in the treatment of acute pelvic inflammatory disease. A comparative study.

Abstract
Sixty patients with acute uncomplicated pelvic infection were treated with cefoxitin or ampicillin alone, the purpose being to show that a relatively cheap antimicrobial agent (ampicillin) could be used. The groups (30 patients in each) were clinically comparable (P greater than 0,01--Hotelling T-square test). In the first group 2 g ampicillin was administered intravenously on admission followed by 1 g intravenously 4-hourly, and in the second group 2 g cefoxitin was administered intravenously on admission followed by 1 g intravenously every 8 hours. A good response was obtained in both groups. On the basis of cost ampicillin would seem to be the treatment of choice in uncomplicated acute pelvic infection.
AuthorsJ A de Beer, J van den Ende, H J Odendaal
JournalSouth African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde (S Afr Med J) Vol. 64 Issue 19 Pg. 733-6 (Oct 29 1983) ISSN: 0256-9574 [Print] South Africa
PMID6353623 (Publication Type: Clinical Trial, Comparative Study, Journal Article, Randomized Controlled Trial)
Chemical References
  • Cefoxitin
  • Ampicillin
Topics
  • Acute Disease
  • Adolescent
  • Adult
  • Ampicillin (therapeutic use)
  • Cefoxitin (therapeutic use)
  • Clinical Trials as Topic
  • Female
  • Humans
  • Pelvic Inflammatory Disease (drug therapy, microbiology)
  • Random Allocation

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