HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Treatment of Gilles de la Tourette syndrome with pimozide.

Abstract
The results of this clinical study of 31 patients with Tourette syndrome suggest that pimozide is more effective and induces fewer side effects than haloperidol in some patients. The clinical advantages of pimozide may be associated with its more specific dopamine-blocking properties and the absence of significant norepinephrine effects. The authors recommend further controlled study of exclusive dopamine antagonists in the treatment of Tourette syndrome.
AuthorsA K Shapiro, E Shapiro, G J Eisenkraft
JournalThe American journal of psychiatry (Am J Psychiatry) Vol. 140 Issue 9 Pg. 1183-6 (Sep 1983) ISSN: 0002-953X [Print] United States
PMID6351642 (Publication Type: Clinical Trial, Comparative Study, Journal Article, Research Support, Non-U.S. Gov't)
Chemical References
  • Pimozide
  • Haloperidol
Topics
  • Adolescent
  • Adult
  • Child
  • Clinical Trials as Topic
  • Female
  • Haloperidol (adverse effects, therapeutic use)
  • Humans
  • Male
  • Middle Aged
  • Pimozide (adverse effects, therapeutic use)
  • Tourette Syndrome (drug therapy)

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: