Plasmid coding for drug resistance and production of heat-labile and heat-stable toxins harbored by an Escherichia coli strain of human origin.

Abstract

In a study of enterotoxigenic strains of Escherichia coli isolated from children with diarrhea in São Paulo, Brazil, a new enterotoxin and antibiotic resistance plasmid that carries heat-labile toxin, heat-stable toxin, and drug resistance genes was found. This is the first such plasmid to be found in a human strain of E. coli. The plasmid is nonconjugative, has a molecular weight of at least 54 x 10(6), and is mobilized by the R plasmid present in the host strain.

• Authors: M L Silva, I C Scaletsky, M H Reis, M H Affonso, L R Trabulsi
• Journal: Infection and immunity (Infect Immun) Vol. 39 Issue 2 Pg. 970-3 (Feb 1983) ISSN: 0019-9567 [Print] United States
• PMID: 6339395 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• Anti-Bacterial Agents
• Bacterial Toxins
• Colicins
• Enterotoxins
• Escherichia coli Proteins
• heat stable toxin (E coli)
• heat-labile enterotoxin, E coli

Topics

• Anti-Bacterial Agents (pharmacology)
• Bacterial Toxins
• Colicins (genetics)
• Conjugation, Genetic
• Enterotoxins (genetics)
• Escherichia coli (drug effects, genetics)
• Escherichia coli Proteins
• Humans
• Molecular Weight
• Plasmids
• R Factors