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A double-blind comparison of sulconazole nitrate 1% cream with clotrimazole 1% cream in the treatment of dermatophytoses.

Abstract
Forty patients with dermatophytosis were treated with either sulconazole 1% cream or clotrimazole 1% cream (twenty patients in each group) twice daily for 4 weeks. Overall clinical improvement with respect to baseline at weeks 2, 3 and 4 favoured sulconazole-treated patients (the differences were statistically significant). The weekly mean severity scores for the sulconazole-treated patients for erythema, scaling, fissuring and itching were consistently lower than those for the clotrimazole-treated patients and the differences were statistically significant for erythema and sealing. It was concluded that sulconazole nitrate 1% cream is very effective against various dermatophytoses.
AuthorsA Lassus, S Forström, O Salo
JournalThe British journal of dermatology (Br J Dermatol) Vol. 108 Issue 2 Pg. 195-8 (Feb 1983) ISSN: 0007-0963 [Print] England
PMID6337618 (Publication Type: Clinical Trial, Comparative Study, Journal Article, Randomized Controlled Trial)
Chemical References
  • Imidazoles
  • sulconazole
  • Clotrimazole
Topics
  • Administration, Topical
  • Adult
  • Clinical Trials as Topic
  • Clotrimazole (administration & dosage, therapeutic use)
  • Dermatomycoses (drug therapy)
  • Double-Blind Method
  • Female
  • Humans
  • Imidazoles (administration & dosage, therapeutic use)
  • Male
  • Tinea Pedis (drug therapy)

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