Ketoconazole treatment of nail infection in chronic mucocutaneous candidiasis.

Abstract

Chronic mucocutaneous candidiasis is an immunodeficiency disorder which has significant morbidity due to mucous membrane, skin and nail infection. Attempts at reconstitution of immunological abnormalities have had only limited success. Ketoconazole is a newly available oral antifungal agent with activity against candida species. Prolonged administration of ketoconazole to four children with chronic mucocutaneous candidiasis caused marked improvement at infected sites. Resolution of nail infections took up to 12 months.

• Authors: D M Roberton, C S Hosking
• Journal: Australian paediatric journal (Aust Paediatr J) Vol. 19 Issue 3 Pg. 178-81 (Sep 1983) ISSN: 0004-993X [Print] Australia
• PMID: 6316890 (Publication Type: Case Reports, Journal Article)

Chemical References

• Ketoconazole

Topics

• Adolescent
• Candidiasis (complications)
• Candidiasis, Chronic Mucocutaneous (complications, drug therapy)
• Child
• Child, Preschool
• Female
• Humans
• Infant
• Ketoconazole (therapeutic use)
• Male
• Nail Diseases (drug therapy, etiology)