Translational inhibition of heat-shock induced gene expression in picornavirus-infected Drosophila melanogaster cells.

Abstract

Picornavirus infection of Drosophila melanogaster cells inhibited the appearance of heat-shock induced proteins. Examination of intracellular mRNAs revealed that those coding for heat shock proteins were present in a translationally competent form in infected cells. Inhibition of induced gene expression in infected Drosophila cells therefore involves, but is not necessarily solely mediated by, effects at the level of translation.

• Authors: B Reavy, J S Pullin, N F Moore
• Journal: Microbios (Microbios) Vol. 38 Issue 152 Pg. 91-8 ( 1983) ISSN: 0026-2633 [Print] England
• PMID: 6316114 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• Heat-Shock Proteins
• RNA, Messenger
• Viral Proteins

Topics

• Animals
• Cells, Cultured
• Drosophila melanogaster (genetics)
• Gene Expression Regulation
• Heat-Shock Proteins (genetics)
• Picornaviridae Infections (genetics)
• Protein Biosynthesis
• RNA, Messenger (genetics)
• Viral Proteins (genetics)