[Clinical resistance of herpetic keratitis to antiviral agents (author's transl)].

Abstract

Clinical resistance of herpetic keratitis to antiviral agents constitutes one of the reasons for failure of treatment after their administration. A retrospective study of 42 cases of superficial herpetic keratitis resistant to IDU, IDU and IDC, and Ara-A demonstrated that in 2 out of 3 cases this resistance appeared in patients previously treated locally with antiviral compounds for anterior ocular lesions. Patients resistant to IDU were then treated with Ara-A, and those not responding to Ara-A, with TFT. Resistance may be observed following this new treatment during the subsequent relapses.

• Authors: J Colin, C Chastel, G Baikoff, G Renard
• Journal: Journal francais d'ophtalmologie (J Fr Ophtalmol) Vol. 4 Issue 1 Pg. 57-60 ( 1981) ISSN: 0181-5512 [Print] France
• Vernacular Title: La résistance clinique des kératites herpétiques aux antiviraux.
• PMID: 6260850 (Publication Type: English Abstract, Journal Article)

Chemical References

• Antiviral Agents
• Vidarabine
• Idoxuridine

Topics

• Adolescent
• Adult
• Aged
• Antiviral Agents (pharmacology, therapeutic use)
• Child
• Child, Preschool
• Drug Resistance, Microbial
• Humans
• Idoxuridine (therapeutic use)
• Keratitis, Dendritic (diagnosis, drug therapy)
• Middle Aged
• Recurrence
• Retrospective Studies
• Simplexvirus (drug effects)
• Vidarabine (therapeutic use)