Abstract |
Over the period 1923--72 a total of 305 patients with granulosa-cell, theca-cell tumor and mixed tumor were seen at Radiumhemmet. The commonest symptom was abnormal uterine bleeding. Twenty-three per cent of married women were nulliparous. The menarche seems to have occurred earlier in this group than in the general population. Eight of the granulosa-cell tumor group gave birth to 12 children after treatment for the tumor. Nineteen women with granulosa-cell tumor and 4 with thecoma had received radiotherapy earlier in life for benign lesions. The risk of endometrial cancer was approximately 10 times greater for the women with granulosa- or theca-cell tumor than for the general population. Two hundred and fifty-two patients were given both surgical treatment and radiotherapy. Fifty-three received only surgery (37 granulosa-cell and 16 theca-cell tumors). None of the thecoma patients but 21 per cent of those with granulosa-cell tumor died from their disease. The 5-year survival for the latter group, all stages, was 85 per cent.
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Authors | E Björkholm, F Pettersson |
Journal | Acta obstetricia et gynecologica Scandinavica
(Acta Obstet Gynecol Scand)
Vol. 59
Issue 4
Pg. 361-5
( 1980)
ISSN: 0001-6349 [Print] United States |
PMID | 6255725
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Topics |
- Adolescent
- Adult
- Age Factors
- Aged
- Female
- Follow-Up Studies
- Granulosa Cell Tumor
(mortality, therapy)
- Humans
- Menarche
- Menopause
- Middle Aged
- Ovarian Neoplasms
(mortality, therapy)
- Parity
- Prognosis
- Sweden
- Thecoma
(mortality, therapy)
- Uterine Hemorrhage
(complications)
- Uterine Neoplasms
(complications)
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