Colestipol hydrochloride for treatment of hypercholesterolemia in a family practice: five-year study.

Abstract

Colestipol hydrochloride (Colestid) lowered the serum cholesterol level significantly more than did placebo in hypercholesterolemic patients (21 colestipol, 19 placebo) treated for up to 5 years. In the 21 colestipol-treated patients, the average decrease in serum cholesterol levels was 19 percent during the first year and 23 percent during the second through fifth years. Seven patients (age range, 44 to 59 years) took colestipol for the full 5 years. The data showed a consistent lowering of the serum cholesterol level. The only side effect was constipation.

• Authors: G Ruoff
• Journal: Journal of the American Geriatrics Society (J Am Geriatr Soc) Vol. 26 Issue 3 Pg. 121-6 (Mar 1978) ISSN: 0002-8614 [Print] United States
• PMID: 624819 (Publication Type: Clinical Trial, Controlled Clinical Trial, Journal Article)

Chemical References

• Polyamines
• Cholesterol
• Colestipol

Topics

• Adult
• Cholesterol (blood)
• Colestipol (therapeutic use)
• Family Practice
• Female
• Follow-Up Studies
• Humans
• Hypercholesterolemia (drug therapy)
• Male
• Michigan
• Middle Aged
• Polyamines (therapeutic use)
• Retrospective Studies