Abstract |
The association between histo-compatibility antigens and disease is reviewed, in particular that between HLA-B27 and spondylitic disorders, i.e., ankylosing spondylitis, Reiter's arthritis, psoriatic arthritis, and ankylosing hyperostosis. We determined whether the presence of HLA-B27 predicted specific radiographic findings and, conversely, whether specific radiographic changes predicted antigenic status. The prevalences of the HLA-B27 antigen in our patients were: ankylosing spondylitis, 100%; Reiter's arthritis, 93%; psoriatic arthritis, 55%; and ankylosing hyperostosis, 12%. The only specific radiographic finding associated with B27 positivity was severe spondylitis in psoriasis.
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Authors | T M Schumacher, H K Genant, M J Kellet, J C Mall, K H Fye |
Journal | Radiology
(Radiology)
Vol. 126
Issue 2
Pg. 289-97
(Feb 1978)
ISSN: 0033-8419 [Print] United States |
PMID | 622470
(Publication Type: Journal Article)
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Chemical References |
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Topics |
- Arthritis
(diagnostic imaging, immunology)
- Arthritis, Reactive
(diagnostic imaging, immunology)
- HLA Antigens
(analysis)
- Humans
- Psoriasis
(diagnostic imaging, immunology)
- Radiography
- Spinal Osteophytosis
(diagnostic imaging, immunology)
- Spondylitis, Ankylosing
(diagnostic imaging, immunology)
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