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A study of urinary excretion of biogenic amine metabolites in epilepsy.

Abstract
Urinary total catecholamines, their metabolites, and a metabolite of serotonin have been investigated in 20 patients with epilepsy, and in 10 controls. The levels of total catecholamines, vanillyl mandelic acid and 5-hydroxyindole acetic acid in epileptics were not significantly different from the controls. However, the mean 3-methoxy-4-hydroxyphenylglycol, excretion in cases of epilepsy was significantly increased as compared to the control group. It is concluded that a central catecholaminergic disturbance is involved in the pathogenesis of epilepsy.
AuthorsL Baliga, A Rao, A Raja, S N Rao
JournalActa neurologica Scandinavica (Acta Neurol Scand) Vol. 68 Issue 6 Pg. 413-6 (Dec 1983) ISSN: 0001-6314 [Print] Denmark
PMID6198865 (Publication Type: Journal Article)
Chemical References
  • Biogenic Amines
  • Methoxyhydroxyphenylglycol
  • Hydroxyindoleacetic Acid
  • Homovanillic Acid
Topics
  • Adolescent
  • Adult
  • Biogenic Amines (urine)
  • Epilepsy (urine)
  • Female
  • Homovanillic Acid (urine)
  • Humans
  • Hydroxyindoleacetic Acid (urine)
  • Male
  • Methoxyhydroxyphenylglycol (urine)
  • Middle Aged

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