Angiotensin converting enzyme inhibitors in the treatment of hypertension.

Abstract

Converting enzyme inhibitors appear to be a safe and effective class of drug for treating the entire spectrum of hypertension, from very mild to severe. For the vast majority of patients who do not experience adverse side effects, these drugs appear to be remarkably well tolerated and are without the adverse metabolic and depressive effects associated with other antihypertensive drugs. Many patients report an enhanced feeling of well-being and may even experience euphoria. Whenever possible, CEIs should be used in the lowest possible effective dose in order to achieve maximum therapeutic benefit with a minimum or complete absence of adverse effects.

• Authors: B J Materson
• Journal: Comprehensive therapy (Compr Ther) Vol. 9 Issue 10 Pg. 14-20 (Oct 1983) ISSN: 0098-8243 [Print] United States
• PMID: 6196149 (Publication Type: Journal Article, Review)

Chemical References

• Antihypertensive Agents
• Oligopeptides
• Captopril
• Teprotide

Topics

• Antihypertensive Agents (therapeutic use)
• Captopril (adverse effects, metabolism, pharmacology)
• Drug Eruptions (etiology)
• Dysgeusia (chemically induced)
• Humans
• Hypertension (drug therapy)
• Hypotension (chemically induced)
• Neutropenia (chemically induced)
• Oligopeptides (pharmacology, therapeutic use)
• Proteinuria (chemically induced)
• Teprotide