Abstract |
A comparison of two series of patients with rhe,matic polyarthritis, the one (n = 140) treated with dosage equal to or higher than 900 mg, the other (n = 60) with dosage between 600 and 750 mg, did not reveal significant difference in clinical and biological efficacy. The number of side-effects was not significantly reduced by lower dosage, except for digestive tract disorders. A reduction of dosage does, therefore, not permit less strict supervision and monitoring for side-effects of treatment.
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Authors | J P Camus, J Crouzet, A Prier, A P Leca |
Journal | Revue du rhumatisme et des maladies osteo-articulaires
(Rev Rhum Mal Osteoartic)
Vol. 44
Issue 12
Pg. 721-4
(Dec 1977)
ISSN: 0035-2659 [Print] France |
Vernacular Title | Recherche d'une posologie optimale de la pénicillamine dans le traitement de la polyarthrite rhumatoïde commune. A propos d'une série personnelle de 200 cas. |
PMID | 609877
(Publication Type: Comparative Study, English Abstract, Journal Article)
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Chemical References |
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Topics |
- Arthritis, Rheumatoid
(drug therapy)
- Female
- Humans
- Male
- Middle Aged
- Penicillamine
(administration & dosage, therapeutic use)
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