Pulmonary blastoma: remission with chemotherapy.

Abstract

A 59-year-old man with pulmonary blastoma, who had undergone right-sided pneumonectomy, had a relapse of the tumour 7 months later. Light-microscopic and ultrastructural studies were consistent with recurrence from the primary tumour. Cell kinetic studies revealed a high fraction of tumour cells in the S-phase. Complete remission of the recurrence was obtained within 16 days after initiation of combination chemotherapy consisting of CCNU, vincristine, VP-16 and cyclophosphamide.

• Authors: M H Nissen, M Jacobsen, L Vindeløv, J Olsen, M Rørth
• Journal: European journal of respiratory diseases (Eur J Respir Dis) Vol. 65 Issue 5 Pg. 377-9 (Jul 1984) ISSN: 0106-4339 [Print] Denmark
• PMID: 6086368 (Publication Type: Case Reports, Journal Article)

Chemical References

• Vincristine
• Etoposide
• Lomustine
• Cyclophosphamide

Topics

• Antineoplastic Combined Chemotherapy Protocols (therapeutic use)
• Combined Modality Therapy
• Cyclophosphamide (administration & dosage)
• Etoposide (administration & dosage)
• Humans
• Lomustine (administration & dosage)
• Lung Neoplasms (drug therapy, surgery)
• Male
• Middle Aged
• Neoplasms, Germ Cell and Embryonal (drug therapy, surgery)
• Pneumonectomy
• Vincristine (administration & dosage)