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[Effect of the combined use of pyrogenal and cyclophosphane on experimental tumors].

Abstract
The effect of the combined administration of cyclophosphane and pyrogenal was studied on mice with sarcoma 37 and Ehrlich carcinoma. It has been found that pyrogenal potentiates the antitumor effect of cyclophosphane and reduces the toxic action of this drug, thus making the survival of animals longer.
AuthorsA I Kolosov, R G Krupkin
JournalVoprosy onkologii (Vopr Onkol) Vol. 23 Issue 10 Pg. 90-2 ( 1977) ISSN: 0507-3758 [Print] Russia (Federation)
Vernacular TitleVliianie sochetannogo primeneniia pirogenala i tsiklofosfana na éksperimental'nye opukholi.
PMID595532 (Publication Type: Journal Article)
Chemical References
  • Lipopolysaccharides
  • Pyrogens
  • pyrogenal
  • Cyclophosphamide
Topics
  • Animals
  • Carcinoma, Ehrlich Tumor (drug therapy)
  • Cyclophosphamide (administration & dosage)
  • Drug Evaluation, Preclinical
  • Drug Synergism
  • Drug Therapy, Combination
  • Lipopolysaccharides
  • Mice
  • Neoplasm Transplantation
  • Neoplasms, Experimental (drug therapy)
  • Pyrogens (administration & dosage)
  • Sarcoma 37 (drug therapy)

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