Abstract |
Galactosamine caused changes in the livers of rats that were similar to those seen in human viral hepatitis. In hamsters the changes were characteristic of a typical toxic hepatitis. The response by the liver to galactosamine was very variable in both the rat and the hamster and there was a degree of correlation between the raised transaminase levels and the liver cell damage.
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Authors | R W Pickering |
Journal | Arzneimittel-Forschung
(Arzneimittelforschung)
Vol. 27
Issue 9
Pg. 1684-7
( 1977)
ISSN: 0004-4172 [Print] Germany |
PMID | 579138
(Publication Type: Comparative Study, Journal Article)
|
Chemical References |
- Galactosamine
- Transaminases
|
Topics |
- Animals
- Chemical and Drug Induced Liver Injury
- Cricetinae
- Galactosamine
(adverse effects, pharmacology)
- Liver
(cytology, drug effects)
- Male
- Rats
- Transaminases
(blood)
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