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Detection of mycolic acid in leprous tissue.

Abstract
A method is described for the extraction of mycolic acid from lepromatous leprosy tissues and from tuberculous tissues and its identification by thin layer chromatography. Verification of the mycolic acid extracted and separated by thin layer chromatography was accomplished by infrared spectroscopy. Although the presence of mycolic acid in tissues is not, in itself, diagnostic for leprosy, its demonstration in biopsy tissues might be a useful additional qualitative test if used in conjunction with clinical evidence of the disease.
AuthorsS Devi, E S Stewart-Tull
JournalInternational journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association (Int J Lepr Other Mycobact Dis) Vol. 47 Issue 3 Pg. 484-6 (Sep 1979) ISSN: 0148-916X [Print] United States
PMID573749 (Publication Type: Journal Article)
Chemical References
  • Mycolic Acids
Topics
  • Animals
  • Chromatography, Thin Layer
  • Humans
  • Leprosy (metabolism)
  • Mycolic Acids (metabolism)
  • Spectrophotometry, Infrared
  • Tuberculosis (metabolism)

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