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Hyperglycemic hyperosmolar nonketotic coma following diazoxide, anesthesia and operation.

Abstract
Unsuspected hyperglycemia caused prolonged postanesthetic coma in a nondiabetic patient treated with IV diazoxide and furosemide. The combined effect of these drugs with general anesthesia and surgical stress was postulated as the cause of the hyperglycemia. Blood glucose should be measured during and after general anesthesia in patients who are potential candidates for hyperglycemic hyperosmolar nonketotic coma.
AuthorsB Shin, S I Joseph
JournalAnesthesia and analgesia (Anesth Analg) 1977 Jul-Aug Vol. 56 Issue 4 Pg. 506-8 ISSN: 0003-2999 [Print] United States
PMID560136 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Furosemide
  • Diazoxide
Topics
  • Aged
  • Anesthesia, General (adverse effects)
  • Diabetic Coma (etiology)
  • Diazoxide (adverse effects)
  • Furosemide (adverse effects)
  • Humans
  • Hyperglycemic Hyperosmolar Nonketotic Coma (etiology)
  • Male
  • Surgical Procedures, Operative (adverse effects)

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