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Polykaryocytosis induced by certain arboviruses in monolayers of BHK-21-528 cells.

Abstract
Multinucleated giant cell formation in a clone of BHK-21 cells, BHK-21-528, was tested with certain arboviruses. Eleven out of 19 viruses tested, Chikungunya, Getah, Sagiyama, Sindbis, Western equine encephalitis, St. Louis encephalitis, Japanese encephalitis, West Nile, Bunyamwera, Germiston and California encephalitis virus induced cell fusion after infection. All cases where giant cells were observed during the experiments, involved the B type cell fusion (fusion from within).
AuthorsN Ueba, T Kimura
JournalThe Journal of general virology (J Gen Virol) Vol. 34 Issue 2 Pg. 369-73 (Feb 1977) ISSN: 0022-1317 [Print] England
PMID557074 (Publication Type: Comparative Study, Journal Article)
Topics
  • Animals
  • Arboviruses (growth & development)
  • Cell Fusion
  • Cell Line
  • Cricetinae
  • Kidney

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