[Experience with the combination mezlocillin/oxacillin in severe bacterial infections in a children's surgical ward (author's transl)].

Abstract

Severe bacterial infections accompanying conditions during childhood which demand for surgical intervention mostly are caused by Staph. aureus, E. coli, Klebsiella/Aerobacter or Ps. aeruginosa. 20 patients, 10 of them suffering from a putrid peritonitis, showed a good efficacy of Optocillin (Bay 1-1330), a combination of 6-((R)-2-[3-methylsulfonyl-2-oxo-imidazolidine-1-carboxamido]-2-phenyl-acetamido)-penicillanic acid sodium salt (mezlocillin, Baypen) and 5-methyl-3-phenyl-4-isoxazolylpenicillin (oxacillin, Stapenor), in 85%. Bacteria were eliminated in 79%.

• Authors: R Kurz
• Journal: Arzneimittel-Forschung (Arzneimittelforschung) Vol. 29 Issue 12a Pg. 2014-7 ( 1979) ISSN: 0004-4172 [Print] Germany
• Vernacular Title: Erfahrungen mit einer Mezlocillin-Oxacillin-Kombination bei schweren bakteriellen Infektionen in einer kinderchirurgischen Klinik.
• PMID: 543915 (Publication Type: English Abstract, Journal Article)

Chemical References

• Drug Combinations
• Penicillins
• Mezlocillin
• Oxacillin

Topics

• Adolescent
• Bacterial Infections (blood, drug therapy)
• Child
• Child, Preschool
• Cross Infection (blood, drug therapy)
• Drug Combinations
• Female
• Humans
• Infant
• Male
• Mezlocillin
• Oxacillin (adverse effects, therapeutic use)
• Penicillins (administration & dosage, adverse effects, therapeutic use)