Malignant transformation of a Warthin tumor: case report, review of the literature, and discussion of pathology.

Abstract

Papillary cystadenoma lymphomatosum (Warthin's tumor) is generally considered to be a benign tumor. However, a few well-documented cases of malignant transformation have been reported. In each case, the patient had received radiotherapy to the neck region where the tumor later developed. This paper reports a case of malignant transformation of a papillary cystadenoma lymphomatosum (PCL) in a patient who had not received radiotherapy. Light and electron microscopy documented this transformation and clearly identified the malignant portion of the tumor as having its origin in a benign PCL. The literature is reviewed and a discussion of pathology presented.

• Authors: E H Caldwell, W G Armiger, H M McDonald
• Journal: Annals of plastic surgery (Ann Plast Surg) Vol. 3 Issue 2 Pg. 177-81 (Aug 1979) ISSN: 0148-7043 [Print] United States
• PMID: 543651 (Publication Type: Case Reports, Journal Article)

Topics

• Adenolymphoma (pathology)
• Adult
• Carcinoma (pathology)
• Cell Transformation, Neoplastic
• Epithelium (ultrastructure)
• Head and Neck Neoplasms (pathology)
• Humans
• Male
• Microscopy, Electron
• Mitochondria (ultrastructure)