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Malignant transformation of a Warthin tumor: case report, review of the literature, and discussion of pathology.

Abstract
Papillary cystadenoma lymphomatosum (Warthin's tumor) is generally considered to be a benign tumor. However, a few well-documented cases of malignant transformation have been reported. In each case, the patient had received radiotherapy to the neck region where the tumor later developed. This paper reports a case of malignant transformation of a papillary cystadenoma lymphomatosum (PCL) in a patient who had not received radiotherapy. Light and electron microscopy documented this transformation and clearly identified the malignant portion of the tumor as having its origin in a benign PCL. The literature is reviewed and a discussion of pathology presented.
AuthorsE H Caldwell, W G Armiger, H M McDonald
JournalAnnals of plastic surgery (Ann Plast Surg) Vol. 3 Issue 2 Pg. 177-81 (Aug 1979) ISSN: 0148-7043 [Print] UNITED STATES
PMID543651 (Publication Type: Case Reports, Journal Article)
Topics
  • Adenolymphoma (pathology)
  • Adult
  • Carcinoma (pathology)
  • Cell Transformation, Neoplastic
  • Epithelium (ultrastructure)
  • Head and Neck Neoplasms (pathology)
  • Humans
  • Male
  • Microscopy, Electron
  • Mitochondria (ultrastructure)

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