[Does myocardial damage arise as a result of administration of tocolytic drugs? (author's transl)].

Abstract

Fifty pregnant women admitted consecutively on account of threatened abortion or premature labour and treated with Ritodrine and Verapamil intravenously in the usual dosage were investigated with respect to creatine kinase activity and, in the event of a raised level, its isoenzyme creatine kinase--MB. Determinations were carried out before treatment and, in accordance with expected peak values in case of myocardial necrosis, after 6 and 12 hours. Three pathological values were recorded and these are discussed individually. Furthermore, statistical evaluation of the recorded values showed no significant differences.

• Authors: W Lechner, F Dienstl
• Journal: Wiener klinische Wochenschrift (Wien Klin Wochenschr) Vol. 91 Issue 23 Pg. 798-801 (Dec 1979) ISSN: 0043-5325 [Print] Austria
• Vernacular Title: Myokardschäden unter Tokolyse?
• PMID: 543142 (Publication Type: English Abstract, Journal Article)

Chemical References

• Isoenzymes
• Propanolamines
• Verapamil
• Creatine Kinase
• Ritodrine

Topics

• Adolescent
• Adult
• Cardiomyopathies (chemically induced)
• Creatine Kinase (metabolism)
• Female
• Humans
• Isoenzymes
• Obstetric Labor, Premature (prevention & control)
• Pregnancy
• Propanolamines (adverse effects)
• Ritodrine (adverse effects)
• Verapamil (administration & dosage)