Acquired, transient factor X (Stuart factor) deficiency in patient with mycoplasma pneumonial infection.

Abstract

A case of severe haemorrhagic diathesis due to acquired deficiency of factor X (both immunologically and in procoagulant activity) is presented. The clinical and serological features of this case indicated mycoplasma pneumonial infection. Factor X in the peripheral blood did not appear to be influenced by administration of vitamin K, prothrombin-complex concentrate, fresh plasma or fresh whole blood. Circulating inhibitors of blood coagulation were absent and systemic amyloidosis could not be demonstrated. After 20 d, factor X spontaneously returned to normal. In view of the absence of other known causes of factor X deficiency, a possible relationship with mycoplasma pneumonial infection is suggested.

• Authors: F W Peuscher, W G van Aken, J A van Mourik, A J Swaak, L H Sie, L W Statius van Eps
• Journal: Scandinavian journal of haematology (Scand J Haematol) Vol. 23 Issue 4 Pg. 257-64 (Oct 1979) ISSN: 0036-553X [Print] Denmark
• PMID: 538412 (Publication Type: Case Reports, Journal Article)

Chemical References

• Vitamin K
• Prothrombin

Topics

• Blood Transfusion
• Factor X Deficiency (blood, drug therapy, etiology)
• Hemorrhagic Disorders (drug therapy, etiology, therapy)
• Humans
• Hypoprothrombinemias (etiology)
• Male
• Middle Aged
• Pneumonia, Mycoplasma (blood, complications)
• Prothrombin (therapeutic use)
• Remission, Spontaneous
• Vitamin K (therapeutic use)