A case of hypogonadotropic eunuchoidism associated with familiar periodic paralysis--induction of paralytic attacks by testosterone administration.

Abstract

A case report was made of a 24-year-old man suffering from hypogonadotropic eunuchoidism associated with a hypokalemic type of familiar periodic paralysis. The attacks were observed only during the period of continual administration of the oil solution of 115.7 mg of testosterone enanthate and 20.0 mg of testosterone propionate, intramuscularly as a depot. From the findings on this patient, it was concluded that testosterone might possibly play a role in the occurrence of attacks in the case of periodic paralysis.

• Authors: H Fukui, O Baba, K Akiyama, S Otsuki, M Takata, H Okuma
• Journal: Folia psychiatrica et neurologica japonica (Folia Psychiatr Neurol Jpn) Vol. 33 Issue 4 Pg. 541-6 ( 1979) ISSN: 0015-5721 [Print] Japan
• PMID: 535836 (Publication Type: Case Reports, Journal Article)

Chemical References

• Testosterone

Topics

• Adult
• Eunuchism (complications, drug therapy)
• Humans
• Male
• Paralyses, Familial Periodic (chemically induced)
• Testosterone (administration & dosage, adverse effects)