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Selective recovery from retrograde amnesia produced by hippocampal spreading depression.

Abstract
Injections of potassium chloride into the hippocampus after learning produce temporary disruption of neural activity and retrograde amnesia. Recovery from the amnesia is selective-rats recover from amnesia of events that occurred24 hours before injection but do not recover from amnesia of events that occurred 10 seconds before injection.
AuthorsB S Kapp, A M Schneider
JournalScience (New York, N.Y.) (Science) Vol. 173 Issue 4002 Pg. 1149-51 (Sep 17 1971) ISSN: 0036-8075 [Print] United States
PMID5107280 (Publication Type: Journal Article)
Chemical References
  • Sodium Chloride
  • Potassium Chloride
Topics
  • Amnesia
  • Animals
  • Brain (drug effects)
  • Conditioning, Psychological
  • Drinking Behavior
  • Electroencephalography
  • Electroshock
  • Hippocampus (drug effects, physiology)
  • Humans
  • Injections
  • Male
  • Memory (drug effects)
  • Potassium Chloride (administration & dosage, pharmacology)
  • Rats
  • Rats, Inbred Strains
  • Sodium Chloride (pharmacology)
  • Time Factors

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