Subtypes of depression identified by the KDS-3A: a pilot study.

Abstract

To devise a system of classifying depression subtypes at intake, the authors administered the Kupfer Detre Scale (KDS-3A) to depressed outpatients at intake and after one, three, and six months of treatment with tricyclic antidepressants or lithium carbonate. None of the 10 tricyclic responders scored below 8 on the 14-point chronic anxiety scale at intake while 7 of the 12 lithium responders did, suggesting that any patient scoring below 8 is a probable candidate for lithium therapy. Patients scoring 8 or above on the chronic anxiety scale fell into two categories, those who had a low impulisivity score and responded to tricyclic antidepressants and those who had a high impulsivity score, responded to lithium, and had cyclothymic disorder or emotionally unstable character disorder.

• Authors: P N Wold, K Dwight
• Journal: The American journal of psychiatry (Am J Psychiatry) Vol. 136 Issue 11 Pg. 1415-9 (Nov 1979) ISSN: 0002-953X [Print] United States
• PMID: 495793 (Publication Type: Case Reports, Journal Article)

Chemical References

• Antidepressive Agents, Tricyclic
• Lithium

Topics

• Adult
• Antidepressive Agents, Tricyclic (therapeutic use)
• Anxiety (diagnosis, drug therapy)
• Bipolar Disorder (diagnosis, drug therapy)
• Chronic Disease
• Depression (diagnosis, drug therapy)
• Diagnosis, Differential
• Female
• Humans
• Lithium (therapeutic use)
• Male
• Middle Aged
• Psychiatric Status Rating Scales