Oxolinic acid in urinary tract infection: a multi-centre trial.

Abstract

A single-blind trial of oxolinic acid (750 mg. twice-daily for 14 days) and ampicillin (500 mg. 3-times daily for 14 days) in 60 cases with urinary tract symptoms showed superior results with oxolinic acid: 94% of pathogens were sensitive to oxolinic acid and 69% were sensitive to ampicillin. Sympotomatic relief and bacterial eradication occurred earlier in the oxolinic acid group.

• Authors: B M Guyer, G M Whitford
• Journal: Current medical research and opinion (Curr Med Res Opin) 1974-1975 Vol. 2 Issue 10 Pg. 636-40 ISSN: 0300-7995 [Print] England
• PMID: 4616804 (Publication Type: Clinical Trial, Comparative Study, Controlled Clinical Trial, Journal Article, Randomized Controlled Trial)

Chemical References

• Ampicillin
• Oxolinic Acid

Topics

• Adolescent
• Adult
• Aged
• Ampicillin (therapeutic use)
• Bacterial Infections (drug therapy)
• Clinical Trials as Topic
• Drug Therapy, Combination
• Escherichia coli (isolation & purification)
• Escherichia coli Infections (drug therapy)
• Family Practice
• Female
• Humans
• Male
• Microbial Sensitivity Tests
• Middle Aged
• Oxolinic Acid (adverse effects, therapeutic use)
• Penicillin Resistance
• Recurrence
• Time Factors
• Urinary Tract Infections (drug therapy)