HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Leydig cell tumor of testis.

Abstract
In adult patients with Leydig cell tumor of the testis, endocrinologic signs occur in 30 per cent of the cases and often precede the onset of a palpable testicular mass. Gynecomastia is the most common endocrinologic manifestation and probably is due to increased estrogen secretion by the Leydig cells. In the patient with adrenogenital syndrome and testicular enlargement it is difficult to distinguish Leydig cell tumor from adrenal rest hypertrophy. Four patients with Leydig cell tumor and endocrinologic manifestations are discussed; three are adults who presented with gynecomastia and the fourth is a patient with congenital adrenogenital syndrome. In the adult patient inguinal orchiectomy is the treatment of choice, while in the patient with adrenogenital syndrome initial management by high-dose steroid suppression should be attempted prior to testicular exploration.
AuthorsA A Caldamone, V Altebarmakian, I N Frank, C A Linke
JournalUrology (Urology) Vol. 14 Issue 1 Pg. 39-43 (Jul 1979) ISSN: 0090-4295 [Print] United States
PMID452218 (Publication Type: Case Reports, Journal Article)
Topics
  • Adrenal Cortex Neoplasms (diagnosis)
  • Adrenal Hyperplasia, Congenital (etiology, therapy)
  • Adrenal Rest Tumor (diagnosis)
  • Adult
  • Diagnosis, Differential
  • Gynecomastia (etiology, therapy)
  • Humans
  • Leydig Cell Tumor (complications, diagnosis, pathology, therapy)
  • Male
  • Testicular Neoplasms (complications, diagnosis, pathology, therapy)

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: